| 17268114 |
Takashima J, Ikeda Y, Komiyama K, Hayashi M, Kishida A, Ohsaki A: New constituents from the leaves of Morinda citrifolia. Chem Pharm Bull. 2007 Feb;55(2):343-5.
A new iridoid glycoside, citrifoside (1), and a new anthraquinone, 1,5,15-trimethylmorindol (2), together with 24 known compounds, were isolated from the leaves of Morinda citrifolia. The structures of the new compounds were elucidated by spectral data. 1,5,15-Trimethylmorindol (2) did not show significant cytotoxic activity by itself but showed cytotoxicity when combined with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), while citrifoside (1) did not show any activity even with TRAIL. |
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