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Yang WM, Liu JK, Hu L, Dong ZJ, Wu WL, Chen ZH: Antioxidant properties of natural p-terphenyl derivatives from the mushroom Thelephora ganbajun. Z Naturforsch C. 2004 May-Jun;59(5-6):359-62. The antioxidant activity in vitro of three poly (phenylacetyloxy)-substituted 1,1':4',1"-terphenyl compounds from the edible mushroom Thelephora ganbajun were investigated. The IC50 values of compounds 1-3 for lipid peroxidation in rat liver homogenate were 400, 48, 54 microM, respectively. Compounds 1-3 increased superoxide dismutase (SOD) activity with EC50 values of 182, 74, 204 microM. They were also assessed on the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity with EC50 values of 49, 1233, 55 microM. |
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