| ID | 1090 |
|---|---|
| Name | angiotensin converting enzyme 2 |
| Synonyms | ACE 2; ACE related carboxypeptidase; ACE2; ACEH; Angiotensin I converting enzyme (peptidyl dipeptidase A) 2; Angiotensin converting enzyme 2; Angiotensin converting enzyme 2 precursor; Angiotensin converting enzyme homolog… |
| ID | 477 |
|---|---|
| Name | biphenyl |
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) |
|---|---|---|
| 18243695 | Deaton DN, Graham KP, Gross JW, Miller AB: Thiol-based angiotensin-converting enzyme 2 inhibitors: P1' modifications for the exploration of the S1' subsite. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1681-7. Epub 2008 Jan 18. Explorations of the S (1') subsite of ACE2 via modifications of the P (1') methylene biphenyl moiety of thiol-based metalloprotease inhibitors led to improvements in ACE2 selectivity versus ACE and NEP, while maintaining potent ACE2 inhibition. |
82(1,1,1,2) |