| 9772697 |
Peng SH, Cui YY, Zhou TH: [Studies on metabolism of 6-methoxy butyl phthalide by rat liver microsomes]. Yao Xue Xue Bao. 1996;31(7):539-42.
The in vitro biotransformation of 6-methoxy butyl phthalide (MBP) by phenobarbital induced rat liver microsomes was investigated by GC/MS and GC/MS with TMS derivatization. Three major metabolites of MBP were identified as 3-OH-MBP, 6-OH-butyl phthalide and gamma-OH-MBP. A less polar metabolite was tentatively identified as an epoxidation product. |
62(0,2,2,2) |