Protein Information

ID 595
Name glyceraldehyde 3 phosphate dehydrogenase
Synonyms CDABP0047; G3PD; GAPD; GAPD protein; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; GAPD proteins; Glyceraldehyde 3 phosphate dehydrogenases

Compound Information

ID 935
Name acifluorfen
CAS 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid

Reference

PubMed Abstract RScore(About this table)
16664219 Wettlaufer SH, Alscher R, Strick C: Chloroplast-Diphenyl Ether Interactions II. Plant Physiol. 1985 Jun;78(2):215-220.
Acifluorfen, a p-nitrodiphenyl ether herbicide, is inhibitory to those photosynthetic functions that require a functioning chloroplast envelope. Functions involving the stroma are also affected. Acifluorfen does not lyse intact spinach chloroplasts, yet does increase the sensitivity of CO (2)-dependent O (2) evolution to exogenous inorganic phosphate without directly affecting the function of the phosphate translocator. Acifluorfen penetrates into the chloroplast stroma in a light-independent fashion. Once inside, it causes the inactivation of light and dithiothreitol-activated fructose 1,6-bisphosphatase. Light-activated glyceraldehyde-3-phosphate dehydrogenase (NADP) is also inactivated by acifluorfen.These data suggest that acifluorfen stimulates a pathway for inactivation of fructose 1,6-bisphosphatase and glyceraldehyde 3-phosphate dehydrogenase (NADP) which uses oxygen as a terminal oxidant and which involves thioredoxin and ferredoxin-thioredoxin reductase.
81(1,1,1,1)