Protein Information

ID 1953
Name factor XIII (protein family or complex)
Synonyms FSF; Factor XIII; Fibrin stabilizing factor; Fibrin stabilizing factors

Compound Information

ID 953
Name monochloroacetic acid
CAS 2-chloroacetic acid

Reference

PubMed Abstract RScore(About this table)
6126311 Ghidalia W, Vendrely R, Montmory C, Coirault Y: Cross induced coagulations between human and crustacean clotting factors. Comp Biochem Physiol A Comp Physiol. 1982;72(4):741-5.
Considerations on the clotting processes.. 1. Cross induced coagulations show that human factor XIII and crustacean coagulin are to some extent functionally equivalent and may be substituted for each other. 2. In crustacea, fibrinogen and coagulin appear as in situ activated products since they are both able to react with non-activated human clotting factors. 3. The coagulin catalyzed transamidation which stabilizes the clot and renders it insoluble in 1-5% monochloroacetic acid solutions seems to be the basic reaction of the clotting process in the animals in which coagulation occurs. 4. The possibility of a two step clotting in crustacea is discussed.
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