Protein Information

ID 813
Name erythropoietin
Synonyms EP; EPO; Epoetin; Erythropoietin; Erythropoietin precursor; Epoetins; Erythropoietins; Erythropoietin precursors

Compound Information

ID 965
Name ferrous sulfate
CAS sulfuric acid iron(2+) salt (1:1)

Reference

PubMed Abstract RScore(About this table)
18098311 Skoner JM, Wax MK: Microvascular free-tissue transfer for head and neck reconstruction in Jehovah's Witness patients. Head Neck. 2008 Apr;30(4):455-60.
BACKGROUND: Jehovah's Witnesses' religious convictions disallow blood transfusion. Major surgery in these patients is therefore problematic. The objective of this study is to describe our experience with microvascular reconstruction of complex head and neck defects in Jehovah's Witness patients. METHODS: This was a retrospective review of all Jehovah's Witnesses' patients undergoing head and neck free-flap reconstruction at a tertiary academic referral center from 1997 to 2006. RESULTS: Five Jehovah's Witnesses patients underwent a total of 7 free-flap reconstructions (6 radial, 1 rectus). Four flaps were immediate: 1 osteocutaneous radial forearm, 2 fasciocutaneous radial forearm, and 1 rectus abdominus myocutaneous. One fasciocutaneous radial forearm flap was staged. Two patients were planned secondary reconstructions, both facsciocutaneous radial forearm. Iron supplements and/or erythropoietin were administered perioperatively in 6 of the 7 microvascular reconstructions. Selective external carotid embolization was performed preoperatively in 1 patient. Hematocrit levels were 36% to 46% preoperatively and 30% to 41% postoperatively. Immediate postoperative hematocrit decline was 5.2% (3.0% to 6.0%). No transfusions or blood products were administered. CONCLUSIONS: Our case series supports the feasibility of head and neck free-flap reconstruction in these challenging patients.
1(0,0,0,1)