Protein Information

ID 759
Name ferritin (protein family or complex)
Synonyms Ferritin; Ferritins

Compound Information

ID 965
Name ferrous sulfate
CAS sulfuric acid iron(2+) salt (1:1)

Reference

PubMed Abstract RScore(About this table)
1501568 Klingshirn LA, Pate RR, Bourque SP, Davis JM, Sargent RG: Effect of iron supplementation on endurance capacity in iron-depleted female runners. Med Sci Sports Exerc. 1992 Jul;24(7):819-24.
The purpose of this investigation was to examine the effects of oral iron supplementation on endurance performance in initially iron-depleted, nonanemic female distance runners. Eighteen iron-depleted (serum ferritin less than 20 ng.ml-1, hemoglobin greater than or equal to 12 g.dl-1) women (22-39 yr) performed a VO2max test and an endurance run to exhaustion. Subjects were pair-matched on the basis of endurance time and then randomly assigned to an iron supplement or a placebo group. Following supplementation, the iron group had a significantly higher (P = 0.03) mean serum ferritin concentration (23.4 vs 15.7 ng.ml-1) and lower (P = 0.04) mean total iron-binding capacity than the placebo group. Both groups increased their time to exhaustion (25.5% and 22.2% for the iron and placebo groups, respectively) but were not significantly different (P = 0.72) from each other. There were also no differences (P greater than 0.05) between the groups with respect to lactate concentrations and physiological measures taken during the two exercise tests. The results of this study suggest that 8 wk of oral iron supplementation improves iron status in iron-depleted female distance runners, but does not enhance endurance capacity.
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