Protein Information

ID 186
Name hemoglobin (protein family or complex)
Synonyms Hemoglobin; Hemoglobins

Compound Information

ID 1390
Name acrylonitrile
CAS 2-propenenitrile

Reference

PubMed Abstract RScore(About this table)
9827881 Yaneva S, Zlatev Z, Totcheva T: Hematological changes in sailors from chemical cargo tankers. J Appl Toxicol. 1989 Feb;9(1):53-7.
The group investigated consisted of 179 sailors from chemical cargo tankers, with an average age of approximately 40 years and duration of special service of between 2-6 years. They were divided into risk groups in accordance with the exposure index. The study comprised 18 voyages, transporting more than 50 chemical substances, mainly benzene, ethyl benzene, acrylonitrile, aniline, acetone, etc. MATERIAL AND METHODS: Erythrocytes, hematokrit, hemoglobin, erythrocyte indices, erythrocyte morphology, leukocytes, leukocyte formula, platelets were determined in venous blood, collected at the end of each voyage. RESULTS: Anemia syndrome, leukocytosis with neutropenia and activation of lymphocytes and monocytes were determined. The observed changes followed the 'exposure-response' relationship. The frequency rate of the deviations varied from 21% for the first risk group, to 10% for the fourth risk group. High correlation between the changes in peripheral blood and the parameters 'special service duration' and 'number of voyages' was determined.
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