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Zabrodskii PF, Germanchuk VG, Kirichuk VF, Karpenko NI: Effect of tetrachloromethane on the immune system. Bull Exp Biol Med. 2004 Jan;137(1):47-9. Acute poisoning with tetrachloromethane in a dose of 0.75 LD (50) suppressed humoral and cell immune reactions in Wistar rats. Immunotoxicity of tetrachloromethane is realized via initiation of lipid peroxidation and inhibition of acetylcholine esterase in T lymphocytes and alpha-naphthyl AS-acetate esterase and alpha-naphthyl butyrate esterase in splenocytes. |
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