| 18078039 |
Sapozhnikova TA, Zarudii FS, Baschenko NZh, Makara NS, Khisamutdinova RIu, Gabdrakhmanova SF, Ivanova NA, Nazarov VS: [Hepatoprotective effect of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol]. Eksp Klin Farmakol. 2007 Jul-Aug;70(4):30-1.
2-Demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol (11-DMP) produces antioxidant effect on the models of toxic hepatitis induced by paracetamol and carbon tetrachloride. The drug normalizes the lipid peroxidation (LPO) prosess in rat liver of the rat and the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the rat blood, thus demonstrating hepatoprotective action. |
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