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Gao JC, Zhang JC, Chen Y, Yang MS, Xiao PG: [Study on chemical constituents from rhizomes of Actaea asiatica] . Zhongguo Zhong Yao Za Zhi. 2007 Nov;32(21):2256-8. OBJECTIVE: To investigate the chemical constituents of the rhizomes of Actaea asiatica in order to obtain a more comprehensive understanding of its effective components. METHOD: Compounds were separated by silica gel chromatography, RP-C18 chromatography and semi-preparative high performance liquid chromatography, and their structures were established by spectral analysis and chemical evidence. RESULT: Six compounds were isolated from the ethyl acetate extract. Their structures were identified as 25-O-acetylcimigenol (1), 12beta-hydroxycimigenol (2), 23-epi-26-deoxyactein (3), 27-deoxyacetylacteol (4), 26-deoxycimicifugenin (5) and beta-sitosterol (6). CONCLUSION: All these compounds mentioned above were isolated from the plant for the first time. |
6(0,0,1,1) |