| 15842749 |
Kuroda N, Sako A, Ohyama K, Akiyama S, Nakashima K: Preparation and characterization of modified 3-aminopropylsilyl silica phases with 1,8-naphthalic anhydrides in HPLC. J Chromatogr Sci. 2005 Mar;43(3):116-20.
Modified 3-aminopropylsilyl silica stationary phases with 1,8-naphthalic anhydrides [3-(1,8-naphthalimido) propyl (NAIP), 3-(4-amino-1,8-naphthalimido) propyl (4A-NAIP), 3-(3-nitro-1,8-naphthalimido) propyl (3N-NAIP), and 3-(4-nitro-1,8-naphthalimido) propyl modified silyl silica gel (4N-NAIP)] are prepared in a single reaction. Chromatographic properties of these phases are characterized using various solutes including monosubstituted benzenes, alkyl benzenes, and polycyclic aromatic hydrocarbons (PAHs) in high-performance liquid chromatography. Even though the retention in these NAIPs is mainly based on the reversed-phase mode, 3N- and 4N-NAIP show a remarkable recognition toward aromatic hydrocarbons, which is attributed to their strong pi-pi interaction. Furthermore, the recognition ability is according to the molecular planarity and non-linearity of PAHs. Subsequently, 3N- and 4N-NAIP has a distinct selectivity from octadecyl silica and, therefore, will be a valuable alternative for a separation or a solid-phase extraction of aromatic compounds. |
33(0,1,1,3) |