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Lucas-Heron B, Loirat MJ, Ollivier B: Severe mitochondrial anomaly in dystrophic mouse skeletal muscle. . Neurosci Lett. 1988 Jul 19;90(1-2):147-51. Mitochondrial fractions were isolated from skeletal muscle of control (C57 BL 6J dy/+) and dystrophic (C57 BL 6J dy/dy) mice, and enzymatic activities (cytochrome c oxidase, rotenone-insensitive NADH cytochrome c reductase) were determined. After electrophoretic separation, calcium-binding proteins were identified. An important anomaly was observed in the mitochondria of dystrophic muscle, i.e., a considerable reduction of a specific calcium-binding protein (61,000 Da mol. wt.). |
6(0,0,1,1) |