Protein Information

ID 62
Name glutathione reductase
Synonyms GLUR; GR; GRD 1; GRD1; GRase; GSR; Glutathione reductase; GRases…

Compound Information

ID 183
Name lindane
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference

PubMed Abstract RScore(About this table)
8882386 Descampiaux B, Leroux JM, Peucelle C, Erb F: Assay of free-radical toxicity and antioxidant effect on the Hep 3B cell line: a test survey using lindane. Cell Biol Toxicol. 1996 Feb;12(1):19-28.
The content of reduced glutathione and of glutathione disulfide as well as the activities of glutathione reductase, glutathione peroxidase, glutathione S-transferases, catalase and superoxide dismutases were determined in human hepatoma Hep 3B cells in relation to free-radical toxicity in order to appreciate the defense capacities of these cells compared to data on normal hepatocytes. When Hep 3B cells were exposed to lindane, a known inducer of free-radical production, superoxide dismutase activity appeared as the best-adapted cellular parameter for early detection of the resulting free-radical toxicity.
1(0,0,0,1)