Protein Information

ID 95
Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

ID 1493
Name phosphamidon
CAS 2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate

Reference

PubMed Abstract RScore(About this table)
3188364 Awal MA, Malik JK, Sandhu HS: Measurement by spectrophotometer of blood cholinesterases inactivation following single oral doses of phosphamidon in Bubalus bubalis. Vet Hum Toxicol. 1988 Oct;30(5):444-6.
The effect of phosphamidon on blood cholinesterases (ChE) was investigated in male buffalo calves following single oral doses of 20, 40 and 80 mg/kg body wt. Phosphamidon at all 3 doses levels significantly inactivated erythrocyte and plasma ChE (66-98 and 67-89%, respectively) within 8-12 hr of administration. The inhibition was dose dependent, and the extent of inactivation of blood ChE correlated well with severity of toxicity following all phosphamidon doses.
87(1,1,2,2)