Protein Information

ID 381
Name bradykinin
Synonyms Alpha 2 thiol proteinase inhibitor; BDK; Bradykinin; KNG; KNG 1; KNG1; Kininogen; Kininogen 1 precursor…

Compound Information

ID 333
Name chloralose
CAS

Reference

PubMed Abstract RScore(About this table)
11499012 Chao DM, Shen LL, Cao YX, Li P: [Inhibitory effect of electroacupuncture on the cardiovascular response evoked by applying bradykinin on the gallbladder]. Sheng Li Xue Bao. 1999 Apr;51(2):175-80.
The effects of electroacupuncture (EA) on the pressor response and reversible myocardial dysfunction induced by application of bradykinin (BK) on the gallbladder were studied in cats anesthetized with alpha-chloralose. The cardiovascular responses evoked by application of BK included a pressor response, an increase of LVP and its dP/dtmax, tachycardia and a decrease of local wall motion of the left ventricle with a supplying branch of the left anterior descending coronary artery ligated beforehand. Following EA of bilateral Neiguan acupionts, the pressor response of BK was inhibited, while the regional left ventricle myocardial dysfunction was alleviated significantly. The effects of EA were reversed by i.v. injection of naloxone (0.4 mg/kg). Our results indicate that EA has an inhibitory effect on the BK-induced pressor and ischemic dysfunction, which may be related with endogenous opioid peptide.
7(0,0,1,2)