| 7552339 |
Wong MK, Hill JM, Kaufman MP: Pressor responses to stimulation of non-NMDA receptors in the superficial laminae of the cat spinal cord. Brain Res. 1995 Jun 12;683(1):149-52.
Microinjection of L-glutamate (109 mM; 12-18 nl) or AMPA (150-300 microM; 12 nl) into the superficial laminae of the L7 dorsal horn of decerebrate or chloralose anesthetized cats significantly increased mean arterial pressure. In contrast, microinjection of NMDA (300 microM; 12 nl) had no effect on mean arterial pressure. The pressor response to L-glutamate microinjection was blocked by prior microinjection of CNQX, an antagonist to non-NMDA receptors, but not by AP-5, an antagonist to NMDA receptors. We conclude that stimulation of non-NMDA receptors in the superficial laminae of the lumbar dorsal horn increases arterial blood pressure. |
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