Protein Information

ID 595
Name glyceraldehyde 3 phosphate dehydrogenase
Synonyms CDABP0047; G3PD; GAPD; GAPD protein; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; GAPD proteins; Glyceraldehyde 3 phosphate dehydrogenases

Compound Information

ID 1792
Name α-chlorohydrin
CAS 3-chloro-1,2-propanediol

Reference

PubMed Abstract RScore(About this table)
6861971 Jones AR, Stevenson D: Formation of the active antifertility metabolite of (S)-alpha-chlorohydrin in boar sperm. Experientia. 1983 Jul 15;39(7):784-5.
The male antifertility agent (S)-alpha-chlorohydrin (I) is metabolized by boar sperm to (S)-3-chlorolactaldehyde (II) by an enzyme that is involved in the oxidation of glycerol to glyceraldehyde. The presence of glycerol decreases the activity of this enzyme towards (S)-alpha-chlorohydrin in vitro thereby preventing the formation of (S)-3-chlorolactaldehyde, an inhibitor of glyceraldehyde 3-phosphate dehydrogenase in boar sperm.		 1(0,0,0,1)