| 6732507 |
Osicka-Koprowska A, Lipska M, Wysocka-Paruszewska B: Effects of chlorfenvinphos on plasma corticosterone and aldosterone levels in rats. Arch Toxicol. 1984 Mar;55(1):68-9.
Plasma corticosteroids concentrations, in rats intoxicated with chlorfenvinphos (p.o. single dose 6.15 mg/kg), were investigated. A significant increase of corticosterone was observed at 1 and 3 h and aldosterone from 1 to 6 h after treatment. Brain and blood AChE activity was diminished to about 10-30% for up to 24 h, with maximal inhibition in brain at 2 h after treatment. Maximal increase in plasma corticosteroids levels occurred within 1 h, while the brain AChE was only slightly inhibited at that time. Results suggest that changes in plasma corticosteroids are not related to the decrease of AChE activity in brain. |
2(0,0,0,2) |