849441 |
Sikorski MM, Cerna J, Rychlik I, Legocki AB: Peptidyl transferase activity in wheat germ ribosomes. Biochim Biophys Acta. 1977 Mar 2;475(1):123-30. Effect of some antibiotics.. The formation of N-acetyl-leucyl-puromycin in a "fragment reaction" catalyzed by 80 S ribosomes from wheat germ was characterized. The reaction product was identified by high-voltage electrophoresis. The fragment reaction is inhibited by sparsomycin, blasticidin S, gougerotin and to a lesser degree by amicetin and tetracycline. Formation of an acLeu-pentanucleotide-ribosomes complex was strongly stimulated by sparsomycin. |
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