Protein Information

ID 57
Name chitinase
Synonyms CHI 3; CHI3; CHIT; CHIT 1; CHIT1; Chitinase; Chitinase 1; Chitotriosidase…

Compound Information

ID 374
Name diflubenzuron
CAS

Reference

PubMed Abstract RScore(About this table)
20229097 Stara J, Erban T, Hubert J: The effect of chitin metabolic effectors on the population increase of stored product mites. Exp Appl Acarol. 2010 Mar 13.
The study tested the effect of the chitin metabolic effectors, teflubenzuron, diflubenzuron, and calcofluor, and a combination of a chitinase and soybean trypsin inhibitor (STI) on the population growth of eight species of stored product mites under laboratory conditions. The compounds were incorporated into the diets of the mites in concentrations ranging from 0.01 to 50 mg g (-1). The final populations of mites were observed after 21 days of growth in controlled conditions. Diflubenzuron and calcofluor suppressed the growth of all the tested species more effectively than the other compounds. The doses required to suppress the mite populations to 50% (rc (50)) in comparison to the control ranged from 0.29 to 12.68 mg g (-1) for diflubenzuron and from 1.75 to 37.7 mg g (-1) for calcofluor, depending on the mite species. When tested at the highest concentration (10 mg g (-1)), teflubenzuron also suppressed all of the tested mite species in comparison to the control. The addition of chitinase/STI into the diet influenced population growth in several ways. When the highest concentration of chitinase in a cocktail of chitinase and STI (12.5 mg g (-1) of diet) was compared to the control, populations of Acarus siro, Aleuroglyphus ovatus and Aeroglyphus robustus decreased significantly, whereas populations of Tyroborus lini and Sancassania rodionovi increased significantly. The sensitivity of species to the tested compounds differed among species. The most tolerant species was S. rodionovi, the most sensitive was A. ovatus. The results confirmed that calcofluor and diflubenzuron have a toxic effect on stored product mites.
33(0,1,1,3)