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Csaba G, Pallinger E: A general response to stressors by the unicellular Tetrahymena: effect of stress on the hormone levels. Cell Biochem Funct. 2008 Oct;26(7):797-800. Hormone (ACTH, endorphin, serotonin and T (3)) content of the unicellular Tetrahymena was studied by using immunocytochemical and flow cytometry methods. The cells were previously treated with different concentrations of salts (NaCl or KCl for 1 h), were kept in low (+4 degrees C) or high (+37 degrees C) temperature for 1 h and were treated with formaldehyde or ethanol. High concentrations of salts (20 mg ml (-1) medium), all levels (0.1, 0.05, 0.01%) of formaldehyde and high temperature almost doubled the hormone contents and 0.1% alcohol also significantly elevated them. The experiments call attention to the presence of a general adaptation syndrome (GAS)-like phenomenon at a unicellular level and points to the possibility of deduction of GAS to a low level of phylogeny. |
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