| 2511899 |
Ghosh P, Bhattacharya S, Bhattacharya S: Impact of nonlethal levels of Metacid-50 and carbaryl on thyroid function and cholinergic system of Channa punctatus. Biomed Environ Sci. 1989 Jun;2(2):92-7.
With regard to brain acetylcholinesterase and acetylcholine and serum triiodothyronine (T3) and thyroxine (T4) profiles, a biphasic response pattern was elicited in Channa punctatus chronically exposed to nonlethal doses of locally used pesticides, namely, Metacid-50 and Carbaryl. Data revealed that these xenobiotics caused significant inhibition of brain acetylcholinesterase activity and a decrease in thyroxine level accompanied by a concurrent increase in acetylcholine accumulation and T3 level. It is surmised that Metacid-50 and Carbaryl influence both neural and hormonal functions. |
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