| 1981826 |
Reddy MS, Jayaprada P, Rao KV: Impact of methylparathion and malathion on cholinergic and non-cholinergic enzyme systems of penaeid prawn, Metapenaeus monoceros. Biochem Int. 1990 Nov;22(4):769-79.
The nervous tissue AChE, BUChE and glutaminase activity levels were significantly inhibited, whereas glutamine synthetase activity, acetylcholine and glutamine contents were increased significantly following the sublethal exposure of prawn, Metapenaeus, monoceros to methylparathion and malathion. During OPI exposure ammoniagenesis was triggered by increased deamination of purines and oxidative deamination of glutamate. This results in the hyperammonemia. As a consequence of hyperammonemia, the OPI exposed prawn tissue have adopted the suitable mechanisms to detoxity the ammonia by enhancing the synthesis of urea and glutamine. From the study, it has been observed that 10 days of reclamation period is not enough but the prawn nervous tissue showed efficient mechanisms for the detoxification or biodegradation of OPI molecules, which will pave way for the successful survival prawns. |
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