| 4006833 |
Prasada Roa KS, Ahammad Sahib IK, Ramana Rao KV: Methyl parathion (O-O-dimethyl O-4-nitrophenyl thiophosphate) effects on whole-body and tissue respiration in the teleost, Tilapia mossambica (Peters). Ecotoxicol Environ Saf. 1985 Jun;9(3):339-45.
The respiratory parameters of a freshwater teleost, Tilapia mossambica Peters, were studied under sublethal intoxication of methyl parathion. The rate of oxygen consumption by whole fish and selected tissues decreased during a 48-hr time-course study. The activities of the respiratory enzymes succinate dehydrogenase, malate dehydrogenase, and cytochrome-c oxidase also decreased considerably under methyl parathion exposure in muscle, gill, liver, and brain tissues. These results suggest that methyl parathion has a profound effect on the oxidative metabolism of the fish which results in low ATP turnover, possibly due to its influence on the respiratory center of the brain. |
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