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Kagan IuS, Kokshareva NV, Savateev NV, Liniuchev MN, Sergeev VV: [Effect of benzonal on the resistance of animals to the action of organophosphorus and carbamic compounds]. Farmakol Toksikol. 1983 Sep-Oct;46(5):100-3.
The inductor of microsomal enzymes, benzonal (20 mg/kg) produces an overt preventive and treatment-preventive action in acute and subacute poisoning with organophosphorus (DDVP, parathion, TEPP, chlorophos) and carbamic (pirimor, sevin) compounds. As regards the efficacy benzonal is not inferior to phenobarbital (14 mg/kg). Pretreatment with benzonal averts the development of the neuromuscular blockade and normalizes spontaneous activity of the myoneural synapse of rats and cats poisoned with pirimor and parathion. |
6(0,0,1,1) |