| 12735970 |
Kothari KK, Raghuraman K, Pillarsetty NK, Hoffman TJ, Owen NK, Katti KV, Volkert WA: Syntheses, in vitro and in vivo characterization of a 99mTc-(I)-tricarbonyl-benzylamino-dihydroxymethyl phosphine (NP (2)) chelate. Appl Radiat Isot. 2003 May;58(5):543-9.
Studies were performed to study the complexation chemistry of 99mTc (CO)(+)(3) with a new tridentate amino-dihydroxymethyl phosphine (NP (2)) ligand with the 99mTc (CO)(3)(OH (2))(+)(3) synthon at tracer levels. A single, well-defined 99mTc (CO)(3) NP (2) complex is formed at pH 7.5 within 10 min at 60 degrees C that exhibits high in vitro and in vivo stability. |
1(0,0,0,1) |