Protein Information

ID 75
Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

ID 312
Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference

PubMed Abstract RScore(About this table)
10413874 Oie S, Kamiya A, Tomita M, Katayama A, Iwasaki A, Miyamura S: Efficacy of disinfectants and heat against Escherichia coli O157:H7. Microbios. 1999;98(389):7-14.
The bactericidal activity of disinfectants and hot water against ten Escherichia coli O157:H7 strains, which were isolated from faeces of patients with enterohaemorrhagic E. coli infection, were evaluated and showed different DNA patterns. After exposure to 0.1% benzalkonium chloride, 0.1% chlorhexidine gluconate containing a nonionic surfactant, and 80% (v/v) ethanol, 99.99% of viable bacterial cells were killed at 20 degrees C within 15 s irrespective of the presence or absence of 0.1% albumin. On the other hand, after exposure to hot water, 99.99% of the bacterial cells were killed within 15 s at 70 degrees C. These results suggest that benzalkonium chloride, chlorhexidine gluconate containing a nonionic surfactant, ethanol, and hot water at 70 degrees C or more are effective for disinfection of E. coli O157:H7 in hospitals.
6(0,0,1,1)