| 6384078 |
Wheeler PR, Bharadwaj VP, Katoch VM, Kannan KB: Lactate dehydrogenase in Mycobacterium leprae grown in armadillo liver. . Int J Lepr Other Mycobact Dis. 1984 Sep;52(3):371-6.
Lactate dehydrogenase (LDH) was detected in extracts of untreated and NaOH-treated Mycobacterium leprae. Since armadillo liver LDH isoenzymes with a similar electrophoretic mobility were shown to be considerably more sensitive to inhibition by oxamate than LDH in M. leprae extracts, it was confirmed that M. leprae grown in armadillo liver has its own LDH. Neither the activity of LDH in M. leprae nor its electrophoretic mobility supported the tentative suggestion that an "anomolous" LDH isoenzyme in infected skin biopsies was in fact an M. leprae-derived enzyme. |
83(1,1,1,3) |