| 12775472 |
Tsumura Y, Ishimitsu S, Saito I, Sakai H, Tsuchida Y, Tonogai Y: Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan. Food Addit Contam. 2003 Apr;20(4):317-24.
Duplicate hospital diet samples obtained over 1 week in 2001 were analysed to estimate the daily intake of plasticizers and the results were compared with those obtained in 1999. The plasticizers quantified in this study were: dibutyl phthalate, butylbenzyl phthalate (BBP), di (2-ethylhexyl) phthalate (DEHP), diisononyl phthalate (DINP), di (2-ethylhexyl) adipate (DEHA), diisononyl adipate (DINA) and O-acetyl tributyl citrate (ATBC). Dipropyl, dipentyl, dihexyl and dicyclohexyl phthalate were also analysed but not detected. The analytical procedure for this follow-up study was essentially the same as in the previous one. Detection limits were 0.1-15.6 ng g (-1) for each plasticizer. One-week duplicate diet samples provided by three hospitals in three remote prefectures of Japan were analysed as individual meals. DEHP was detected at 6-675 ng g (-1) in 62 of 63 meals, significantly lower levels compared with those detected in 1999. Levels of DEHA and DINP also decreased. The mean intake of plasticizers estimated from all samples was 160 microg DEHP day (-1), 12.5 microg DEHA day (-1), 4.7 microg DINP day (-1) and 3.4 microg BBP day (-1). Levels of DINA were relatively high in meals from one hospital: in those meals, the average daily intake was 1338 microg day (-1). Those of ATBC were also higher in meals from another hospital: the average daily intake was 1228 microg day (-1). The sources of DINA and ATBC can be cling-film or sausage packaging. |
8(0,0,1,3) |