| 3629488 |
Mandel'baum AIa: [Are any drug admixtures except iron preparations required in the treatment of iron deficiency anemia?]. Ter Arkh. 1987;59(6):119-24.
The aim was to estimate the efficacy of multimodality therapy of iron deficiency anemia with vitamins combined with iron salts and to compare the results of this therapy with that including iron salts only. Besides the results of therapy using iron preparations administered per os and in injections were compared. Altogether 250 women were entered in this study. Chronic posthemorrhagic iron deficiency anemia was diagnosed in 175 patients, in 75 iron deficiency anemia developed against a background of pregnancy 250 women were divided into 10 groups. The last 3 groups included pregnant women. The selection in the first 7 and last 3 groups was randomized. The rate of increment of hemoglobin, erythrocytes and serum iron did not differ in the groups of patients receiving in addition to iron vitamins B12 and B6, copper sulfate, the combination of iron with the vitamin B group and copper sulfate. In the group receiving iron for injection the rate of increment of hemoglobin did not almost differ from that in the study groups, however it was slightly higher. Similar results were obtained for the pregnant women. Subsequent therapy after hemoglobin normalization was shown to make therapeutic results more stable. A conclusion was made of inappropriateness of the use of iron combined with other preparations in view of numerous cases of side-effects and danger of the development of siderosis of internal organs as a result of erroneous drug administration. The use of iron preparations for injections was recommended only in disturbed intestinal absorption of iron. |
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