| 2113847 |
Cicero R, Gallone A, Maida I, Pintucci G: Effects of copper on the tyrosinase of liver pigment cells from Rana esculenta L. Comp Biochem Physiol B. 1990;96(2):393-7.
1. The liver pigment cells of R. esculenta L. constitute a peculiar pigment cell system of histiocytic nature and contain a tyrosinase-like activity localized in the protein component of melanosomes. 2. The effects of addition and/or removal of Cu on the DOPA-oxidase activity of the system were studied. 3. It was concluded that: (a) this tyrosinase behaves as a Cu-enzyme; (b) Cu could be involved in the regulation of the enzyme activity; and (c) mixtures of apoenzyme and active enzyme coexist in the melanosomes. |
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