Protein Information

ID 742
Name coproporphyrinogen oxidase
Synonyms COX; HCP; CPO; CPOX; CPX; Coprogen oxidase; Coproporphyrinogen oxidase; Coproporphyrinogen oxidase variant…

Compound Information

ID 483
Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference

PubMed Abstract RScore(About this table)
2079105 Adjarov DG: Decreased activity of liver coproporphyrinogen oxidase in hexachlorobenzene-induced porphyria. Exp Pathol. 1990;40(2):117-22.
A 2.5-time decrease of hepatic coproporphyrinogen oxidase activity was established in mice fed for 8 weeks with a diet containing 0.02% hexachlorobenzene. The enzyme activity was determined by a newly developed technique measuring directly the unconverted substrate, coproporphyrinogen III, with reverse phase HPLC (high-performance liquid chromatography) after its spontaneous oxidation to coproporphyrin.
12(0,0,2,2)