ID | 1270 |
---|---|
Name | beta secretase |
Synonyms | ASP2; App beta secretase; Asp 2; Asp2; Aspartyl protease 2; BACE; BACE 1; BACE1… |
ID | 1819 |
---|---|
Name | piperazine |
CAS | piperazine |
PubMed | Abstract | RScore(About this table) |
---|---|---|
18770069 | Laras Y, Garino C, Dessolin J, Weck C, Moret V, Rolland A, Kraus JL: New N (4)-substituted piperazine naphthamide derivatives as BACE-1 inhibitors. J Enzyme Inhib Med Chem. 2009 Feb;24(1):181-7. Synthesis and enzymatic evaluation of new series of N (4)-substituted piperazine naphthamide derivatives as BACE-1 inhibitors for the treatment of Alzheimer's disease are reported. |
62(0,2,2,2) |