Protein Information

ID 1270
Name beta secretase
Synonyms ASP2; App beta secretase; Asp 2; Asp2; Aspartyl protease 2; BACE; BACE 1; BACE1…

Compound Information

ID 1819
Name piperazine
CAS piperazine

Reference

PubMed Abstract RScore(About this table)
18770069 Laras Y, Garino C, Dessolin J, Weck C, Moret V, Rolland A, Kraus JL: New N (4)-substituted piperazine naphthamide derivatives as BACE-1 inhibitors. J Enzyme Inhib Med Chem. 2009 Feb;24(1):181-7.
Synthesis and enzymatic evaluation of new series of N (4)-substituted piperazine naphthamide derivatives as BACE-1 inhibitors for the treatment of Alzheimer's disease are reported.
62(0,2,2,2)