ID | 3805 |
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Name | serotonin receptor |
Synonyms | 5 hydroxytryptamine receptor 6; serotonin receptor; 5 HT 6; 5 HT6; 5 hydroxytryptamine (serotonin) receptor 6; 5 hydroxytryptamine 6 receptor; HTR 6; HTR6… |
ID | 1819 |
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Name | piperazine |
CAS | piperazine |
PubMed | Abstract | RScore(About this table) |
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17892934 | Tasler S, Kraus J, Wuzik A, Muller O, Aschenbrenner A, Cubero E, Pascual R, Quintana-Ruiz JR, Dordal A, Merce R, Codony X: Discovery of 5-HT6 receptor ligands based on virtual HTS. . Bioorg Med Chem Lett. 2007 Nov 15;17(22):6224-9. Epub 2007 Sep 8. Based on a pharmacophore alignment on a 5-HT (6) ligand applying 4SCan technology, a new lead series was identified and further structurally investigated. K (i) s down to 8 nM were achieved. |
2(0,0,0,2) |