ID | 59 |
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Name | alkaline phosphatase |
Synonyms | ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase… |
ID | 182 |
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Name | endosulfan |
CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
PubMed | Abstract | RScore(About this table) |
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3388749 | Dikshith TS, Raizada RB, Kumar SN, Srivastava MK, Kaushal RA, Singh RP, Gupta KP: Effect of repeated dermal application of endosulfan to rats. Vet Hum Toxicol. 1988 Jun;30(3):219-24. Dermal application of endosulfan to male (18.75, 37.50 and 62.50 mg/kg/day) and female (9.83, 19.66 and 32.0 mg/kg/d) rats for 30 days produced hyperexcitability, tremor, dyspnea and salivation. There were no deaths. The signs of toxicity subsided after a week. Endosulfan produced no significant changes in the organ:body weight ratio. No significant changes were seen in the histological and hematological indices. However, a significant decrease in liver GOT and GPT and serum GPT activities and a significant rise in serum alkaline phosphatase and total protein were recorded in the endosulfan-treated animals. There were no changes in LDH. Residue analysis revealed higher levels of total endosulfan in fatty tissues of rats receiving the highest dose of endosulfan. |
6(0,0,1,1) |