| ID | 68 |
|---|---|
| Name | glucose 6 phosphate dehydrogenase |
| Synonyms | 6 phosphogluconolactonase; GDH; G6PDH; Glucose 6 phosphate dehydrogenase; GDH/6PGL endoplasmic bifunctional protein; GDH/6PGL endoplasmic bifunctional protein precursor; Glucose 1 dehydrogenase; Glucose dehydrogenase… |
| ID | 182 |
|---|---|
| Name | endosulfan |
| CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
| PubMed | Abstract | RScore(About this table) |
|---|---|---|
| 8588293 | Sinha N, Narayan R, Shanker R, Saxena DK: Endosulfan-induced biochemical changes in the testis of rats. Vet Hum Toxicol. 1995 Dec;37(6):547-9. Adult male rats were exposed to 0, 2.5, 5.0 or 10.0 mg endosulfan/kg body weight through oral intubation for 70 d. Decreased sperm counts in the cauda epididymis and reduced intratesticular spermatid counts associated with elevation in the activities of specific testicular marker enzymes (sorbitol dehydrogenase, lactic dehydrogenase, gamma glutamyl transpeptidase, and glucose-6-phosphate dehydrogenase) were seen in all the endosulfan-dosed groups. Endosulfan caused impairment in testicular functions by altering activities of the enzymes responsible for spermatogenesis, thereby influencing intratesticular spermatid count and causing low sperm production and sperm deformity. |
31(0,1,1,1) |