Text mining Term | calmodulin |
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UniProt ID | CALM_RAT |
Name |
Calmodulin CaM |
Gene Names |
Calm3
|
Taxonomy | Rattus norvegicus |
Function |
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+), AND MASS SPECTROMETRY. Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). |
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Subcellular location |
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules (By similarity). |
GO:0043548 | phosphatidylinositol 3-kinase binding | MF |
GO:0005246 | calcium channel regulator activity | MF |
GO:0048306 | calcium-dependent protein binding | MF |
GO:0000922 | spindle pole | CC |
>gi|6978591|ref|NP_036650.1| calmodulin [Rattus norvegicus] MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL TMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE EFVQMMTAK |
Ensembl Gene |
ENSRNOT00000064679 ENSRNOT00000022603 |
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UniGene |
Rn.5968 Rn.4166 Rn.2892 Rn.216430 |
PDB |
3CLN 1G4Y 3IFK 2PQ3 3EK7 3EKJ 3EVR 3EKH 1QX7 1QX5 3BXK 3EK4 2HQW 2YGG 3BXL 3B32 1NIW 3EVV 3EVU 3EK8 |
RefSeq |
NP_036650.1 NP_114175.1 NP_059022.1 |
Pfam |
PF00036 |