phosphoserine phosphatase

General Information (Source: NCBI Gene,UniProt)

Text mining Term phosphoserine phosphatase
UniProt ID SERB_RAT
Name PSPase
O-phosphoserine phosphohydrolase
PSP
Phosphoserine phosphatase
Gene Names Psph
Taxonomy Rattus norvegicus

General annotation

Function Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity).
Subcellular location

Gene Ontology

GO:0004647 phosphoserine phosphatase activity MF
GO:0000287 magnesium ion binding MF
GO:0005737 cytoplasm CC
GO:0006564 L-serine biosynthetic process BP
GO:0009612 response to mechanical stimulus BP
GO:0031667 response to nutrient levels BP
GO:0033574 response to testosterone stimulus BP
GO:0019717 synaptosome CC
GO:0005509 calcium ion binding MF

Sequence

>gi|57527332|ref|NP_001009679.1| phosphoserine phosphatase [Rattus norvegicus]
MVSHSELRKLFCSADAVCFDVDSTVIREEGIDELAKFCGVEAAVSEMTRRAMGGALPFKDALTERLALIQ
PSRDQVQRLLAEHPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVAAKLNIPTTNVFANRLKFYFN
GEYAGFDETQPTAESGGKGKVIGFLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAK
WYITDFVELLGELEE

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000001228
UniGene Rn.8734
PDB
RefSeq NP_001009679.1
Pfam PF00702