endothelin 3

General Information (Source: NCBI Gene,UniProt)

Text mining Term endothelin 3
UniProt ID EDN3_MOUSE
Name PPET3
Preproendothelin-3
Endothelin-3
ET-3
Gene Names Edn3
Taxonomy Mus musculus

General annotation

Function Endothelins are endothelium-derived vasoconstrictor peptides.
Subcellular location Secreted.

Gene Ontology

GO:0019229 regulation of vasoconstriction BP
GO:0048070 regulation of developmental pigmentation BP
GO:0030182 neuron differentiation BP
GO:0008284 positive regulation of cell proliferation BP
GO:0030318 melanocyte differentiation BP
GO:0001755 neural crest cell migration BP

Sequence

>gi|6681267|ref|NP_031929.1| endothelin-3 precursor [Mus musculus]
MEPGLWLLLGLTVTSAAGLVPCPQSGDSGRASVSQGPPEAGSERGCEETVAGPGERIVSPTVALPAQPES
AGQERAPGRSGKQEDKGLPAHHRPRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRESLRGKR
SLGPVPESSQPSPWTRLRCTCMGADDKACAHFCARTRDVTSYSGRAERPAAEEMRETGGPRQRLMSRTDK
AHRP

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000029030
UniGene Mm.9478
PDB
RefSeq NP_031929.1
Pfam PF00322