cyclooxygenase 2

General Information (Source: NCBI Gene,UniProt)

Text mining Term cyclooxygenase 2
UniProt ID Q543K3_MOUSE
Name Prostaglandin-endoperoxide synthase 2
Gene Names Ptgs2
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0006979 response to oxidative stress BP
GO:0008217 regulation of blood pressure BP
GO:0020037 heme binding MF
GO:0004666 prostaglandin-endoperoxide synthase activity MF
GO:0004601 peroxidase activity MF
GO:0042640 anagen BP
GO:0043005 neuron projection CC
GO:0005737 cytoplasm CC
GO:0019371 cyclooxygenase pathway BP

Sequence

>gi|31981525|ref|NP_035328.2| prostaglandin G/H synthase 2 precursor [Mus musculus]
MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPT
PNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPP
VADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGL
GHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGL
VPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPE
LLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRV
AGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELY
PALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKG
CPFTSFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Mm.292547
PDB 3NT1
3NTB
RefSeq NP_035328.2
Pfam PF03098