amino acid transporter

General Information (Source: NCBI Gene,UniProt)

Text mining Term amino acid transporter
UniProt ID S38A7_MOUSE
Name Putative sodium-coupled neutral amino acid transporter 7
Gene Names Slc38a7
Synonyms:Snat7
Taxonomy Mus musculus

General annotation

Function Mediates sodium-dependent transport of amino acids. Substrate preference is ranked l-glutamine > l-histidine > l- serine > l-alanine > l-aspargine > l-aspartic acid > l-glutamic acid > l-methionine > l-leucine > l-glycine.
Subcellular location Membrane; Multi-pass membrane protein. Note=In neurons, located in soma and axons.

Gene Ontology

GO:0030424 axon CC
GO:0015191 L-methionine transmembrane transporter activity MF
GO:0005313 L-glutamate transmembrane transporter activity MF
GO:0015183 L-aspartate transmembrane transporter activity MF
GO:0015186 L-glutamine transmembrane transporter activity MF
GO:0043025 neuronal cell body CC
GO:0015194 L-serine transmembrane transporter activity MF
GO:0006814 sodium ion transport BP
GO:0005290 L-histidine transmembrane transporter activity MF
GO:0015180 L-alanine transmembrane transporter activity MF
GO:0015190 L-leucine transmembrane transporter activity MF
GO:0015182 L-asparagine transmembrane transporter activity MF
GO:0016021 integral to membrane CC

Sequence

>gi|27370116|ref|NP_766346.1| putative sodium-coupled neutral amino acid transporter 7 [Mus musculus]
MAQVSINSDYSEWASSTDAGERARLLQSPCVDVVPKSEGEASPGDPDSGTTSTLGAVFIVVNACLGAGLL
NFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTF
GTCIAFLIIIGDQQDKIIAVMSKEPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASFLSVV
GTWYVTAIIIIKYIWPDKEMRPGDILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPEVKTWGGV
VTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEG
LWLRYKGMPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFIFPGLCLIQAKL
SEMEEVKPASWWALVSYGVLLVTLGAFIFGQTTANAIFVDLLA

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Database Cross Reference

Ensembl Gene ENSMUST00000040481
UniGene Mm.29267
PDB
RefSeq NP_766346.1
Pfam PF01490