phenylethanolamine N methyltransferase

General Information (Source: NCBI Gene,UniProt)

Text mining Term phenylethanolamine N methyltransferase
UniProt ID PNMT_RAT
Name PNMTase
Phenylethanolamine N-methyltransferase
Noradrenaline N-methyltransferase
Gene Names Pnmt
Taxonomy Rattus norvegicus

General annotation

Function Converts noradrenaline to adrenaline.
Subcellular location

Gene Ontology

GO:0046500 S-adenosylmethionine metabolic process BP
GO:0071375 cellular response to peptide hormone stimulus BP
GO:0043204 perikaryon CC
GO:0005625 soluble fraction CC
GO:0005737 cytoplasm CC
GO:0030425 dendrite CC
GO:0042415 norepinephrine metabolic process BP
GO:0045472 response to ether BP
GO:0001666 response to hypoxia BP
GO:0030325 adrenal gland development BP
GO:0043195 terminal button CC
GO:0045471 response to ethanol BP
GO:0009414 response to water deprivation BP
GO:0042418 epinephrine biosynthetic process BP
GO:0071363 cellular response to growth factor stimulus BP
GO:0043196 varicosity CC
GO:0035176 social behavior BP
GO:0032868 response to insulin stimulus BP
GO:0009409 response to cold BP
GO:0014823 response to activity BP
GO:0046498 S-adenosylhomocysteine metabolic process BP
GO:0071549 cellular response to dexamethasone stimulus BP
GO:0050909 sensory perception of taste BP
GO:0004603 phenylethanolamine N-methyltransferase activity MF

Sequence

>gi|158081717|ref|NP_113714.1| phenylethanolamine N-methyltransferase [Rattus norvegicus]
MDRGSDPKHTAGMDSDSDPGQAEVALAYQRFEPRAYLRNNYAPPRGDLSNPDGVGPWKLRCMAQVFATGE
VSGQVLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELGLWLREEPGAFDWSVYSQHVCLIEDKGES
WQEKERQLRARVKRVLPIDVHKPQPLGASGLAPLPADALVSAFCLEAVSPDLPSFRQALYHITTLLRPGG
NLLFIGALEESWYLAGEARLSVVPVSEEEVREALVCSGYEVRDLRTYIMPAHLRTGVDDVKGIFFAWAQK
IEVQV

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Database Cross Reference

Ensembl Gene
UniGene Rn.202604
PDB
RefSeq NP_113714.1
Pfam PF01234