P40

General Information (Source: NCBI Gene,UniProt)

Text mining Term P40
UniProt ID SEPT3_RAT
Name G-septin
P40
Neuronal-specific septin-3
Gene Names Sept3
Taxonomy Rattus norvegicus

General annotation

Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Subcellular location Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Cell junction, synapse. Note=In cultured hippocampal neurons, predominantly localized to presynaptic terminals.

Gene Ontology

GO:0019717 synaptosome CC
GO:0005829 cytosol CC
GO:0042734 presynaptic membrane CC
GO:0005525 GTP binding MF
GO:0007049 cell cycle BP
GO:0031105 septin complex CC
GO:0030054 cell junction CC

Sequence

>gi|9507085|ref|NP_062248.1| neuronal-specific septin-3 [Rattus norvegicus]
MSKGLPEARTDTAMSELVPEPRPKPAVPMKPVSINSNLLGCIGIDTIIEQMRKKTMKTGFDFNIMVVGQS
GLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGIKMKLTVIDTPGFGDQINNENCWE
PIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNVIPVIAKAD
TMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGR
KTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVP
ATPCPTAE

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Database Cross Reference

Ensembl Gene
UniGene Rn.48803
PDB
RefSeq NP_062248.1
Pfam PF00735