cyclin A

General Information (Source: NCBI Gene,UniProt)

Text mining Term cyclin A
UniProt ID CCNA2_MOUSE
Name Cyclin-A
Cyclin-A2
Gene Names Ccna2
Taxonomy Mus musculus

General annotation

Function Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
Subcellular location Nucleus. Cytoplasm. Note=Cytoplasmic when associated with SCAPER (By similarity).

Gene Ontology

GO:0007067 mitosis BP
GO:0005737 cytoplasm CC
GO:0045893 positive regulation of transcription, DNA-dependent BP
GO:0001940 male pronucleus CC
GO:0051301 cell division BP
GO:0000079 regulation of cyclin-dependent protein kinase activity BP
GO:0019901 protein kinase binding MF
GO:0001939 female pronucleus CC

Sequence

>gi|161353444|ref|NP_033958.2| cyclin-A2 [Mus musculus]
MPGTSRHSGRDAGSALLSLHQEDQENVNPEKLAPAQQPRAQAVLKAGNVRGPAPQQKLKTRRVAPLKDLP
INDEHVTAGPSWKAVSKQPAFTIHVDEAEETQKRPAELKETECEDALAFNAAVSLPGARKPLTPLDYPMD
GSFESPHAMDMSIVLEDKPVNVNEVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVE
VGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQ
VLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAF
HLALYTVTGQSWPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETL
SV

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Database Cross Reference

Ensembl Gene ENSMUST00000029270
UniGene Mm.4189
PDB 3QHW
3QHR
RefSeq NP_033958.2
Pfam PF02984
PF00134