annexin V

General Information (Source: NCBI Gene,UniProt)

Text mining Term annexin V
UniProt ID ANXA5_RAT
Name VAC-alpha
Annexin-5
Thromboplastin inhibitor
Anchorin CII
CBP-I
Placental anticoagulant protein I
Calphobindin I
Placental anticoagulant protein 4
Lipocortin V
Endonexin II
PP4
Annexin A5
PAP-I
Annexin V
Vascular anticoagulant-alpha
Gene Names Anxa5
Synonyms:Anx5
Taxonomy Rattus norvegicus

General annotation

Function This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Subcellular location

Gene Ontology

GO:0007596 blood coagulation BP
GO:0051260 protein homooligomerization BP
GO:0042995 cell projection CC
GO:0014704 intercalated disc CC
GO:0005737 cytoplasm CC
GO:0030971 receptor tyrosine kinase binding MF
GO:0005509 calcium ion binding MF
GO:0042383 sarcolemma CC
GO:0005544 calcium-dependent phospholipid binding MF
GO:0050819 negative regulation of coagulation BP
GO:0043065 positive regulation of apoptotic process BP

Sequence

>gi|6978505|ref|NP_037264.1| annexin A5 [Rattus norvegicus]
MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSE
LTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVV
GDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDK
YMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLF
NIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD

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Database Cross Reference

Ensembl Gene
UniGene Rn.3318
PDB 1BC0
1A8B
1BC1
1N42
2H0K
2H0L
1N41
1BCZ
2H0M
1BCW
1G5N
2RAN
2IE7
1N44
1A8A
1BC3
2IE6
1BCY
RefSeq NP_037264.1
Pfam PF00191