beta glucuronidase

General Information (Source: NCBI Gene,UniProt)

Text mining Term beta glucuronidase
UniProt ID BGLR_RAT
Name Beta-glucuronidase
Gene Names Gusb
Synonyms:Gus
Taxonomy Rattus norvegicus

General annotation

Function Plays an important role in the degradation of dermatan and keratan sulfates.
Subcellular location Lysosome.

Gene Ontology

GO:0005529 sugar binding MF
GO:0005764 lysosome CC
GO:0043169 cation binding MF
GO:0004566 beta-glucuronidase activity MF
GO:0005975 carbohydrate metabolic process BP
GO:0005625 soluble fraction CC

Sequence

>gi|158303310|ref|NP_058711.2| beta-glucuronidase precursor [Rattus norvegicus]
MSPRRSVCWFVLGQLLCSCALALQGGMLFPKETPSRELKVLDGLWSFRADYSNNRLQGFEKQWYRQPLRE
SGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVVLRINSAHYYAVVWVNGIHVV
EHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTLPPGTIVYKTDPSMYPKGYFVQDISFDFFNY
AGLHRSVVLYTTPTTYIDDITVTTDVDRDVGLVNYWISVQGSDHFQLEVRLLDEDGKIVARGTGNEGQLK
VPRAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYTLPVGIRTVAVTKSKFLINGKPFYFQGVNKHEDS
DIRGRGFDWPLLIKDFNLLRWLGANSFRTSHYPYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLR
HHLEVMDELVRRDKNHPAVVMWSVANEPVSSLKPAGYYFKTLIAHTKALDPTRPVTFVSNTRYDADMGAP
YVDVICVNSYLSWYHDYGHLEVIQLQLTSQFENWYKMYQKPIIQSEYGADAVSGLHEDPPRMFSEEYQTA
LLENYHLILDEKRKEYVIGELIWNFADFMTNQSPLRVTGNKKGIFTRQRNPKMAAFILRERYWRIANETR
GYGSVPRTQCMGSRPFTF

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.3692
PDB
RefSeq NP_058711.2
Pfam PF02837
PF02836
PF00703