Pr 3

General Information (Source: NCBI Gene,UniProt)

Text mining Term Pr 3
UniProt ID PRTN3_MOUSE
Name Proteinase 3
PR-3
Myeloblastin
Gene Names Prtn3
Taxonomy Mus musculus

General annotation

Function Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters (By similarity).
Subcellular location

Gene Ontology

GO:0004252 serine-type endopeptidase activity MF
GO:0030574 collagen catabolic process BP
GO:0006508 proteolysis BP

Sequence

>gi|31981542|ref|NP_035308.2| myeloblastin precursor [Mus musculus]
MAGSYPSPKGIHPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPGSHFCGGTLIHPRFVLT
AAHCLQDISWQLVTVVLGAHDLLSSEPEQQKFTISQVFQNNYNPEENLNDVLLLQLNRTASLGKEVAVAS
LPQQDQTLSQGTQCLAMGWGRLGTQAPTPRVLQELNVTVVTFLCREHNVCTLVPRRAAGICFGDSGGPLI
CNGILHGVDSFVIRECASLQFPDFFARVSMYVDWIQNVLRGAEP

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000006679
UniGene Mm.2364
PDB
RefSeq NP_035308.2
Pfam PF00089