erythropoietin

General Information (Source: NCBI Gene,UniProt)

Text mining Term erythropoietin
UniProt ID EPO_RAT
Name Erythropoietin
Gene Names Epo
Taxonomy Rattus norvegicus

General annotation

Function Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
Subcellular location Secreted.

Gene Ontology

GO:0001666 response to hypoxia BP
GO:0043627 response to estrogen stimulus BP
GO:0045666 positive regulation of neuron differentiation BP
GO:0005128 erythropoietin receptor binding MF
GO:0005615 extracellular space CC
GO:0070555 response to interleukin-1 BP
GO:0055093 response to hyperoxia BP
GO:0043526 neuroprotection BP
GO:0005179 hormone activity MF
GO:0048678 response to axon injury BP
GO:0033189 response to vitamin A BP
GO:0009651 response to salt stress BP
GO:0032496 response to lipopolysaccharide BP
GO:0043249 erythrocyte maturation BP
GO:0007568 aging BP
GO:0051602 response to electrical stimulus BP
GO:0033574 response to testosterone stimulus BP

Sequence

>gi|8393316|ref|NP_058697.1| erythropoietin precursor [Rattus norvegicus]
MGVPERPTLLLLLSLLLIPLGLPVLCAPPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDT
KVNFYAWKRMKVEEQAVEVWQGLSLLSEAILQAQALQANSSQPPESLQLHIDKAISGLRSLTSLLRVLGA
QKELMSPPDATQAAPLRTLTADTFCKLFRVYSNFLRGKLKLYTGEACRRGDR

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000001914
UniGene Rn.11365
PDB
RefSeq NP_058697.1
Pfam PF00758